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  • Evidence is increasing that every addiction without exception is related to difficulty with the brain's reward center, especially the mesolimbic system. This the main problem regulates reward responses in establishing food and sex, plus in nurturing infants and children. One of the most important neurotransmitters involved with reward responses, both whenever they malfunction and once they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the level of dopamine released in in reaction to a stimulus"(Bostwick & Bucci, 2008).

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